{"id":3358,"date":"2025-09-03T00:03:47","date_gmt":"2025-09-03T03:03:47","guid":{"rendered":"https:\/\/laboratoriounimedical.com\/producto\/guardian-comprimidos-250\/"},"modified":"2025-12-16T16:07:01","modified_gmt":"2025-12-16T19:07:01","slug":"guardian-comprimidos-250","status":"publish","type":"product","link":"https:\/\/laboratoriounimedical.com\/en\/producto\/guardian-comprimidos-250\/","title":{"rendered":"Guardian Tablets 250"},"content":{"rendered":"

Palatable tablets<\/strong><\/p>\n

External antiparasitic in palatable tablets for oral use in dogs. Indicated for the treatment of dogs with infestations of fleas, ticks, and mites of domestic, sarcoptic, and otodectic mange<\/strong>.<\/p>\n

Effect lasts\u00a0for up to 12 weeks.<\/strong><\/p>\n

INSTRUCTIONS FOR USE<\/strong>
\nGuardian is indicated for use in canines.
For adult dogs and puppies over 8 weeks of age weighing more than 2 kg.<\/p>\n

It is indicated for the control of flea infestations (Ctenocephalides felis<\/em>\u00a0and\u00a0Ctenocephalides canis<\/em>) and tick infestations (Ixodes<\/em>\u00a0spp.,\u00a0Rhipicephalus sanguineus<\/em>\u00a0adults and immature stages with immediate activity,\u00a0Amblyomma<\/em>\u00a0spp.). It is also indicated for the control of fleas in cases of flea allergy dermatitis (FAD).<\/p>\n

Guardian is further indicated for the treatment of demodectic mange caused by\u00a0Demodex<\/em>\u00a0spp., sarcoptic mange caused by\u00a0Sarcoptes scabiei<\/em>, and otodectic (aural) mange caused by\u00a0Otodectes<\/em>\u00a0spp.<\/p>\n

In addition to being effective in killing external parasites after treatment, this compound may reduce the risk of transmission of pathogens, such as the cestode\u00a0Dipylidium caninum<\/em>, from infested fleas to susceptible dogs.<\/p>\n

Target parasites include ticks (Ixodes<\/em>\u00a0spp.,\u00a0Rhipicephalus sanguineus<\/em>\u00a0adults and immature stages,\u00a0Amblyomma<\/em>\u00a0spp.), fleas (Ctenocephalides felis<\/em>\u00a0and\u00a0Ctenocephalides canis<\/em>), and mites (Demodex<\/em>\u00a0spp.,\u00a0Sarcoptes scabiei<\/em>, and\u00a0Otodectes cynotis<\/em>).<\/p>\n

FORMULA<\/strong>
\nEach cp contains:
\nFluralaner \u2026\u2026\u2026\u2026\u2026….\u2026………………..\u2026 250 mg
\nExcipientes q.s ….\u2026\u2026\u2026\u2026\u2026………………. 750 mg<\/p>\n

DOSAGE<\/strong>
\nThe dosage is 25-56mg of fluralaner\/kg of body weight, within a weight range. Administer the appropriate tablet according to the animal\u2019s weight, based on its presentations. If the dog weighs more than 40 kg, administer a combination of two or more tablets adjusted to its body weight.<\/p>\n

Guardian 250<\/strong> is indicated for dogs weighing 4,6 to 10 kg.<\/p>\n

\"\"<\/p>\n

 <\/p>\n

Do not break the tablet.<\/strong>
\nit should be supplied with the food.<\/strong><\/p>\n

For flea infestations, administration is at 12-week intervals. The effect on fleas can be observed 8 hours after a flea feeds, and on ticks, 12 hours after a tick feed.<\/p>\n

For the treatment of demodectic mange caused by Demodex sp., a single dose should be administered. In these cases, it should be noted that demodectic mange is a multifactorial disease, so it is recommended to treat any underlying condition.<\/p>\n

For the treatment of sarcoptic mange caused by Sarcoptes scabiei and ear mange caused by Otodectes spp., it should be administered in a single dose. For the treatment of tick infestations (adult and juvenile Ixodes spp. and Rhipicephalus sanguineus, Amblyomma spp.), results may be observed 12 hours after the tick has fed.<\/p>\n

Follow the instructions of the attending veterinarian.<\/p>\n

MECHANISM OF ACTION<\/strong>
\nFluralaner is an acaricide\/insecticide that inhibits the gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels, with significant selectivity for insect neurons over mammalian neurons. This results in the induction of uncontrolled neuronal activity, leading to paralysis and death of fleas and ticks.<\/p>\n

CONTRAINDICATIONS AND ADVERSE EFFECTS<\/strong>
\nGastrointestinal problems such as decreased appetite, vomiting, and diarrhea may occur as adverse effects.
\nOther adverse effects have included excessive salivation, incoordination, and seizures. Do not administer to animals with hypersensitivity to the active ingredient. Administer with caution to animals with a history of seizures or epilepsy.<\/p>\n

PRECAUTIONS<\/strong>
\nDo not give to puppies under 8 weeks old and\/or weighing less than 2 kg. Do not break the tablet.
\nObserve the animal while administering the product to ensure it is swallowed correctly.
\nDo not eat, drink, or smoke while handling this veterinary medicinal product. Wash your hands thoroughly with soap and water immediately after using the product.<\/p>\n

STORAGE<\/b>
\nAlways keep in its original packaging. Store in a cool, dry place away from direct sunlight. Do not store above 30\u00b0C. Keep out of reach of children and pets. Dispose of at your nearest collection center.<\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Fluralaner 250 mg Excipientes c.s.p 750 mg<\/p>\n","protected":false},"featured_media":2981,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_cat":[603,544],"product_tag":[],"class_list":["post-3358","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-products-a-z","product_cat-external-antiparasitic","thumb-has-effect","prod-rating-off"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/product\/3358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/comments?post=3358"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/media\/2981"}],"wp:attachment":[{"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/media?parent=3358"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/product_cat?post=3358"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/product_tag?post=3358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}