{"id":543,"date":"2023-08-07T11:38:56","date_gmt":"2023-08-07T14:38:56","guid":{"rendered":"https:\/\/laboratoriounimedical.com\/producto\/tirovet-4\/"},"modified":"2023-11-29T10:34:17","modified_gmt":"2023-11-29T13:34:17","slug":"tirovet-4","status":"publish","type":"product","link":"https:\/\/laboratoriounimedical.com\/en\/producto\/tirovet-4\/","title":{"rendered":"Tirovet 4"},"content":{"rendered":"<p>Use in canines<br \/>\nLevothyroxine sodium thyroid hormone for hypothyroidism<\/p>\n<p><strong>Indications:<\/strong><br \/>\nIndicated for the treatment of deficiency hypothyroidism thyroid hormone of any etiology. Replacement therapy.<br \/>\n<strong>Dosage:<\/strong><br \/>\nIn dogs the daily dose of 0.02 mg to 0.04 mg per Kg (equivalent to 1 tablet of 0.4 mg for 10 to 20 kg of weight).<\/p>\n<p>Dosage Considerations:<br \/>\nAt the beginning of treatment start with a dose 0.02 mg \/ Kg (1 tablet for 20 Kg of Weight) 2 times a day.<br \/>\nWith a maximum dose of 0.8 mg 2 times a day.<br \/>\nAfter 4-8 weeks, assess the clinical response and measure the level of T4 at 4-6 hours after the dose.<\/p>\n<p>If the clinical response is positive and<br \/>\n1) Low Normal T4: The dose should be increased and rechecked in 4 weeks.<br \/>\n2) T4 Normal high or slightly higher than normal: do not change the dose and check again in 6 months.<br \/>\n3) 40% or more above normal: decrease dose or consider administration once a day and recheck after 4 weeks (if a daily dose leads to the previous level).<\/p>\n<p>If the clinical response is negative and<br \/>\n1) Low normal T4: increase dose and check again in 8 weeks (dose may need to be increased again) move to dosing<br \/>\n3 times a day or re-evaluate the diagnosis.<br \/>\n2) T4 Normal high up to an increase of 40% or more over the normal range:<br \/>\nReassess the diagnosis.<\/p>\n<p><em>Source: Donald C. Plumb Manual of Veterinary Pharmacology Sixth Edition<\/em><\/p>\n<p>Contraindications<br \/>\nContraindicated in patients with acute myocardial infarction, thyrotoxicosis, insufficiency untreated adrenal. It should be used with caution and at a low initial dose in patients with concurrent hypoadrenocorticism (treated), heart disease, diabetes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Levotiroxine 0.4mg<\/p>\n","protected":false},"featured_media":1364,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_cat":[603,548],"product_tag":[],"class_list":["post-543","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-products-a-z","product_cat-hormonals","thumb-has-effect","prod-rating-off"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/product\/543","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/comments?post=543"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/media\/1364"}],"wp:attachment":[{"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/media?parent=543"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/product_cat?post=543"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/laboratoriounimedical.com\/en\/wp-json\/wp\/v2\/product_tag?post=543"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}